Will Armodafinil Show on a Drug Test?

Armodafinil is a wakefulness-promoting agent (or eugeroic) and is prescribed for the treatment of narcolepsy, obstructive sleep apnea/hypopnea syndrome, and shift work disorder. Unlike traditional stimulants such as amphetamine and methylphenidate, armodafinil does not produce a feeling of euphoria and is considered to be non-addictive. It is also known to have a lower potential for abuse than these other stimulants.

Armodafinil is a controlled substance in the United States and Canada, and is classified as a Schedule IV drug. It is not currently approved for use by the Food and Drug Administration (FDA) in the United States, but is available as a prescription drug in other countries. Armodafinil has been shown to produce some positive effects on cognitive function, such as improved attention, working memory, and reaction time. However, further research is needed to confirm its safety and efficacy.

Armodafinil is a white to off-white, crystalline powder that is practically insoluble in water and ether, but soluble in chloroform. It has a molecular weight of 273.35 and a pKa of 9.9. The drug is administered orally and is typically taken in doses of 150 mg to 250 mg per day. It has a half-life of approximately 15 hours.

Armodafinil is a relatively new drug and has not been extensively studied. As such, there is limited information available on its potential for abuse or addiction. However, as with any controlled substance, there is always the potential for abuse and addiction. Armodafinil should be used with caution and only as prescribed by a physician.

Armodafinil, also known as Nuvigil, is a prescription medication used to improve wakefulness in adults who experience excessive sleepiness due to narcolepsy, obstructive sleep apnea, and shift work disorder. Armodafinil is in a class of medications called eugeroics (wakefulness promoting agents). It works by increasing the amount of dopamine and norepinephrine in the brain. Artvigil 150 Mg is a generic form of armodafinil.

How Long Does Armodafinil (Nuvigil) Stay in Your System?

The half-life of armodafinil is about 15 hours, so it will stay in your system for about 7.5 days. However, the effects of the drug can last for up to 25 hours. Therefore, it is important to be very careful when taking armodafinil and to avoid activities that require concentration and coordination, such as driving or operating heavy machinery, until you know how the drug will affect you.

How Long Does Armodafinil Stay in Your Urine, Hair and Blood?

Armodafinil will stay in your urine for about 3 days, in your hair for up to 90 days, and in your blood for about 2 days.

What are the Side Effects of Armodafinil (Nuvigil)?

The most common side effects of armodafinil include headache, nausea, diarrhea, dry mouth, and anxiety. Less common side effects include chest pain, palpitations, and rash. Armodafinil should not be taken by people with a history of seizures or by those who are pregnant or nursing. It is also important to note that armodafinil can increase the risk of high blood pressure and should not be taken by people who are already taking medication for high blood pressure.

Factors That Influence How Long Armodafinil Stays in Your System

The duration of armodafinil in your system is influenced by a variety of factors, including your age, weight, and sex. It is also affected by how much you eat and drink, and the presence of other medications in your system. Armodafinil is metabolized by the liver, so factors that affect liver function, such as alcohol use and viral hepatitis, can also influence how long it stays in your system.

Armodafinil (Nuvigil) Drug Interactions

Armodafinil can interact with a variety of other medications, including antidepressants, antifungals, and HIV medications. It can also interact with other drugs that affect the liver, such as acetaminophen and statins. Be sure to tell your doctor about all the medications you are taking, including over-the-counter medications and supplements, before starting armodafinil.

Half-Life of Armodafinil

The half-life of armodafinil is about 15 hours, so it will stay in your system for about 7.5 days. However, the effects of the drug can last for up to 25 hours.

Medical Disclaimer:  This content is for educational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.


  • Hallare, Jericho; Gerriets, Valerie. “Half Life.” StatPearls, October 6, 2020. Accessed November 15, 2020.
  • Drugs.com. “Nuvigil.” March 1, 2010. Accessed November 15, 2020.
  • NMS Labs. “Modafinil/Armodafinil, Blood.” Accessed November 15, 2020.

Mobile Health Management Services. “What Are the Different Drug Panels?” Accessed November 15, 2020.

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